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OSI-420 Size:Solid 2 mg Smiles: OC(=O)CCNC1=CC(=NC(=N1)C1=CC=CC=N1)N1CCC2=CC=CC=C2CC1

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Description

Smiles: OC(=O)CCNC1=CC(=NC(=N1)C1=CC=CC=N1)N1CCC2=CC=CC=C2CC1

CAS Number: 2169916-18-9

InChiKey: IHHMUBRVTJMLQO-UHFFFAOYSA-N

1007/s12094-018-02025-3

Chayahara N

OSI-420 Size:Solid 2 mg Smiles: OC(=O)CCNC1=CC(=NC(=N1)C1=CC=CC=N1)N1CCC2=CC=CC=C2CC1OSI 420 (CP 473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Product information CAS Number: 183320 51 6 Molecular Weight: 415. 87 Formula: C21H22ClN3O4 Chemical Name: 2 ({4 [(3 ethynylphenyl)amino] 7 (2 methoxyethoxy)quinazolin 6 yl}oxy)ethan 1 ol hydrochloride Smiles: Cl.

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