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MDK-3017 ustat Inhibition of IRE1α-driven pro-survival pathways

SKU: 55214331545

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Description

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

CAS Number: 870087-36-8

the combination of Dasatinib and GNF-2 overcame resistance of BCR/ABL-T315I in all models used in a synergistic manner

TK216 exhibits antilymphoma activity

Stat1•Stat3

MDK-3017 ustat Inhibition of IRE1α-driven pro-survival pathwaysMDK 3017 is a K Ras inhibitor, by binding to K Ras in a hydrophobic pocket that is occupied by Tyr 71 in the apo Ras crystal structure. Product information CAS Number: 84783 01 7 Molecular Weight: 207. 29 Formula: C11H13NOS Chemical Name: (2 Hydroxy phenyl) pyrrolidin 1 yl methanethione Smiles: OC1=CC=CC=C1C(=S)N1CCCC1 InChiKey: QIKLOVZAPGSYNO UHFFFAOYSA N InChi: InChI=1S C11H13NOS c13 10 6 2 1 5 9(10)11(14)12 7 3 4 8 12 h1 2,5 6,13H,3 4,7 8H2

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