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InChiKey: VYXFEFOIYPNBFK-UHFFFAOYSA-N
(-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor
selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor with IC50 of 9
Smiles: CC1=NC(=CS1)/C=C(\C)/[C@@H]1C[C@@H]2O[C@@H]2CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1
It is on the World Health Organization's List of Essential Medicines
Astragalin Catalog No.:M9893-10 InChiKey: VYXFEFOIYPNBFK-UHFFFAOYSA-NAstragalin is a flavonoid with anti inflammatory activity. Astragalin inhibits IL 1 stimulated nitric oxide and prostaglandin E2 (PGE2) production in patient derived osteoarthritis chondrocytes. It also inhibits IL 1 stimulated expression of nitric oxide synthase (NOS) and COX 2 and activation of MAPK and NF B signaling. Astragalin also reduces reactive oxygen species (ROS) production, collagen fiber deposition, and autophagosome formation in the
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