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8-tetrahydropteridin-6-one
11aH-cyclopenta[a]phenanthren-7-yl sodium sulfate
and when doses are 30 and 100 mg/kg
InChiKey: WPHKIQPVPYJNAX-UHFFFAOYSA-N
Formula: C21H31NO6
MG-115 Size:Contact [email protected] for quotation 8-tetrahydropteridin-6-oneMG 115 (Z Leu Leu Nva H) is a potent, reversible peptide aldehyde inhibitor of proteasome chymotrypsin like and caspase like activities. It induces p53 dependent apoptosis. Blockade of proteasomal degradation by MG115 can activate autophagy. Treatment with proteasome inhibitors Z Leu Leu Nva H (MG 115) or Z Leu Leu Leu H (MG 132) prevented the accelerated degradation of these mutant receptors, resulting in increased amounts of the mutant receptors in
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