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AMG 232 Catalog No.:M8600-2 4 μM for the inhibition

SKU: 8401497975

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Description

4 μM for the inhibition of SK2

Chemical Name: 1-(4-((2-aminopyrimidin-4-yl)oxy)phenyl)-3-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)urea

An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers

InChiKey: VWBDGXJRQZDLRV-CSKARUKUSA-N

STAT3-IN-1 (compound 7d) is an excellent

AMG 232 Catalog No.:M8600-2 4 μM for the inhibitionAMG232 is an extremely potent MDM2 inhibitor (SPR KD = 0. 045 nM, SJSA 1 EdU IC50 = 9. 1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA 1 osteosarcoma xenograft model (ED50 = 9. 1 mg kg). AMG232 is currently under clinical development. Product information CAS Number: 1352066 68 2 Molecular Weight: 568. 55 Formula: C28H35Cl2NO5S Synonym: AMG232 AMG 232 Chemical Name: 2 [(3R,5R,6S) 5 (3 chlorophenyl) 6 (4

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