Plague Mare The incredibly easy comparison to Plague Mare is Goblin Chainwhirler, which has been directly in the Standard spotlight ever since its dominant performance at Pro Tour Dominaria
The answer is no
For example, the commander, Isperia, Supreme Judge, may allow you to draw lots of cards if an opponent goes full send at you in combat, but there aren't a lot of ways in the deck to prevent the damage to give yourself time to play those cards
While a very powerful spell that's brilliant for a go-wide deck, the high mana cost of Biorhythm, and the fact that it will sit in your hand, a dead card, for most of the game, has some suggesting it would now be fine in the format
Victor, Valgavoths Seneschal Victor, Valgavoth's Seneschal is bonkers in Yorion, Sky Nomad decks where you get to blink a lot of enchantments at once
A really playable card thats singable just when you need it