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Glucocorticoid receptor agonist - CAS# 1245526-82-2 Catalog No.:M10731-2 Characterization of the novel broad-spectrum

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Description

Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling

BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308

Smiles: O[Bi]1OC2=CC=CC=C2C(=O)O1

InChi: InChI=1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7

or insulin

Glucocorticoid receptor agonist - CAS# 1245526-82-2 Catalog No.:M10731-2 Characterization of the novel broad-spectrumGlucocorticoid receptor agonist, CAS No. 1245526 82 2, is a potent Glucocorticoid receptor agonist. Glucocorticoid receptor agonist acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2. 1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid like anti inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and

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