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PF-3758309 hydrochloride has similar enzymatic potency against the kinase domains of the other group B PAKs (PAK5
PI-103 inhibits phosphorylation of Akt with an IC95 100-fold lower than that for LY294002
10(12):1219-23
ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)
Formula: C25H25F3N4O6
FIIN-3 esine Hydrochloride PF-3758309 hydrochloride has similar enzymaticFIIN 3 is an irreversible inhibitor of FGFR with an IC50 of 13. 1, 21, 31. 4, and 35. 3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Product information CAS Number: 1637735 84 2 Molecular Weight: 691. 61 Formula: C34H36Cl2N8O4 Chemical Name: N (4 {[3 (6 {[4 (4 methylpiperazin 1 yl)phenyl]amino}pyrimidin 4 yl)[(2,6 dichloro 3,5 dimethoxyphenyl)carbamoyl]amino]methyl}phenyl)prop 2 enamide Smiles:
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