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SSR180711 hydrochloride Catalog No.:M33079-C Treatment of the animals with

SKU: 32963067562

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Description

Treatment of the animals with SMI-16a for 5 days per week reduces the growth of tumors by approximately 50% and does not cause a loss of body weight

an imidazoline

Response to a submaximal dose of the CCKB receptor agonist Pentagastrin (100 nM) was dose dependently blocked by the CCKB receptor antagonist L-365

4)25/h11-17

leading to the activation of caspase-9 and -32

SSR180711 hydrochloride Catalog No.:M33079-C Treatment of the animals withSSR180711 hydrochloride is an orally active, selective and reversible 7 acetylcholine nicotinic receptor (n AChRs) partial agonist. SSR180711 hydrochloride can act on rat 7 n AChR (Ki=22 nM; IC50=30 nM) and human 7 n AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long term potentiation (LTP) in the hippocampus. Product information CAS Number: 446031 79 4 Molecular Weight: 361. 66

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