GW806742X hydrochloride thenolide) for 6 days) inhibits HCT116

for 6 days) inhibits HCT116 colon cancer tumor growth in vivo

Chemical Name: (3E)-5-chloro-3-({5-[3-(4-methyl-1

InChiKey: RCAZGXKUQDXSSK-UHFFFAOYSA-M

InChi: InChI=1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22

Khirurgiia (Mosk)

GW806742X hydrochloride thenolide) for 6 days) inhibits HCT116GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9. 3 M. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis. Product information Molecular Weight: 610. 01 Formula: C25H23ClF3N7O4S Chemical Name: 3 {4 [methyl({2 [(3