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21(10):2733-41
InChi: InChI=1S/C19H20ClFN4O3/c1-12-15(21)5-4-14(18(12)20)19(26)22-16-11-13(25(27)28)3-6-17(16)24-9-7-23(2)8-10-24/h3-6
C/C=C1/C[N+]2(C)CC[C@@]34C5=CC=CC=C5N[C@@]23[C@@H](O)C[C@@H]/1[C@@]4(CO)C(=O)OC
CAS Number: 1190021-64-7
PNU-159682 showed > 3
Castanospermine Catalog No.:M13930-10 21(10):2733-41Castanospermine inhibits all forms of and glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine linked lipids). target and glucosidases. IC 50: 1. 2 uM in vitro : Castanospermine, [(1 S,6S,7R,8R,8aR) 1 ,6,7,8 tetrahydroxyoctahydroindolizine] is a potent and specific inhibitor of mammalian and plant and D glucosidases in vitro in vivo: Experiments in vivo with castanospermine, an