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used in the treatment of gout
ROS production
11S)-11-hydroxy-9-methyl-3-oxatricyclo[5
SLIGKV- and SLIGRL- for human and mouse/rat PAR2
CAS Number: 1213269-23-8
GNE-049 at mesylate used in the treatment ofGNE 049 is a highly potent and selective CBP inhibitor with an IC50 of 1. 1 nM in TR FRET assay. GNE 049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. Product information CAS Number: 1936421 41 8 Molecular Weight: 510. 58 Formula: C27H32F2N6O2 Chemical Name: 1 {3 [7 (difluoromethyl) 6 (1 methyl 1H pyrazol 4 yl) 1,2,3,4 tetrahydroquinolin 1 yl] 1 (oxan 4 yl) 1H,4H,5H,6H,7H pyrazolo[4,3 c]pyridin 5 yl}ethan 1 one Smiles:
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