N1C(=NC2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C#N)C1=CC2OCOC=2C=C1Br](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M17489_1634722100.gif?v=1634722101)
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Smiles: C[C@@H](C1CCCCC1)N1C(=NC2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C#N)C1=CC2OCOC=2C=C1Br
After oral dosing
Saccharopine
The affinity of F 11440 for 5-HT1A binding sites (pKi
5 μg of histone H1
EGFR mutant-IN-1 Catalog No.:M17489-C Smiles: C[C@@H](C1CCCCC1)N1C(=NC2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C#N)C1=CC2OCOC=2C=C1BrEGFR mutant IN 1, a 5 methylpyrimidopyridone derivative, is a potent and selective EGFRL858R T790M C797S mutant inhibitor with an IC50 of 27. 5 nM, while being a significantly less potent for EGFRWT (IC50 >1. 0 M). Product information Molecular Weight: 632. 17 Formula: C34H39ClFN7O2 Chemical Name: (R) 6 (2 chloro 3 fluorophenyl) 5 methyl 2 ((3 methyl 4 (4 methylpiperazin 1 yl)phenyl)amino) 8 (1 propionylpiperidin 3 yl)pyrido[2, 3 d]pyrimidin 7(8H) one
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