PubMed PMID: 25516695
GW9508 is active as an agonist at both GPR40 and GPR120
LY3200882 shows potent anti-tumor activity in the orthotopic 4T1-LP model of triple negative breast cancer and this activity correlated with enhanced tumor infiltrating lymphocytes in the tumor microenvironment[1]
alkaline phosphatases and a number of ATPases
Mey Biochem J
INT-777 - CAS# 1199796-29-6 HM-12 PubMed PMID: 25516695INT 777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0. 82 M). INT 777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis. Product information CAS Number: 1199796 29 6 Molecular Weight: 450. 65 Formula: C27H46O5 Synonym: S EMCA INT777 INT 777 Chemical Name: (2S,4R) 4 [(1R,3aS,3bR,4R,5R,5aS,7R,9aS,9bS,11S,11aR) 5 ethyl 4,7,11 trihydroxy 9a,11a dimethyl hexadecahydro