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The gimmick behind them is that they can be played with life instead of mana, a strategy that allows for some immensely broken combos due to all the mana-hoarding one could do

Cards like Ground Seal can protect your graveyard from targeted removal, assuming you dont want to target the cards yourself

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Ursula - Sea Witch Queen also has a nicely thematic ability with You'll Listen To Me!, which disallows other characters from being exerted to sing songs

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You can also protect your board with cards like Flawless Maneuver or Boros Charm