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PTP1B-IN-2 displays more than 40-fold selectivity for PTP1B over SHP-2 and LAR and 15-fold higher selectivity for PTP1B over the highly homologous TCPTP
Smiles: C[C@H]1[C@@H](OC2=C1C=C(/C=C/C)C=C2OC)C1=CC(OC)=C(O)C=C1
Tasisulam (25 or 50 mg/kg
g-PPT (100 nM
4-dichlorophenethyl)-N1
NS5806 048PEG6-Boc PTP1B-IN-2 displays more than 40-foldNS5806, a potent potassium current activator, increases KV4. 3 KChIP2 peak current amplitudes with an EC50 of 5. 3 M. NS5806 slows KV4. 3 and KV4. 2 current dacay in channel complexes containing KChIP2. Product information CAS Number: 426834 69 7 Molecular Weight: 574. 07 Formula: C16H8Br2F6N6O Chemical Name: 3 [3,5 bis(trifluoromethyl)phenyl] 1 [2,4 dibromo 6 (2H 1,2,3,4 tetrazol 5 yl)phenyl]urea Smiles:
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