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CUDC-907 durably inhibits the PI3K-AKT-mTOR pathway and compensatory signaling molecules such as RAF
CAS Number: 1417329-24-8
InChiKey: QBIYUDDJPRGKNJ-UHFFFAOYSA-M
CAS Number: 1118807-13-8
InChiKey: DMIDPTCQPIJYFE-UHFFFAOYSA-N
CID-2011756 - CAS# 638156-11-3 und Library of Histone Demethylase CUDC-907 durably inhibits the PI3K-AKT-mTORCID 2011756, CAS No. 638156 11 3, is a cell active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester induced endogenous PKD1 activation in LNCaP prostate cancer cells. IC50 Value: 100. 7 uM (cellular inhibition of phospho Ser916 PKD1 activity) [1] Target: PKD CID 2011756, has pan PKD inhibitory effects (PKD2 IC50 = 0. 60. 1 uM; PKD3 IC50 = 0. 70. 2 uM) with similar, albeit not identical, potencies which may be expected for an ATP