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CAS Number: 931417-26-4
InChi: InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7
CAS Number: 136174-04-4
InChiKey: WCHWQPTUXDMALZ-ZSCHJXSPSA-N
Naoki Nanashima
INCA-6 Size:Contact [email protected] for quotation CAS Number: 931417-26-4INCA 6 is a selective inhibitor of transcription factor NFAT with Kd value of 0. 8 mM in vitro. NFAT (Nuclear factor of activated T cells) is a general name which is applied to a family of transcription factors that are important in immune response. They are expressed in most immune system cells. Calcium signaling plays an important role in NFAT activation. Calmodulin activates calcineurin (CN) which is a serine threonine phosphatase, then
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