TAK-715 odiamide hydrate C646 was used at 10

C646 was used at 10 µM final concentration in various in vitro assays

3-6H3/b15-13+

Wei-Qing L

Acetazolamide D3 is deuterium labeled Acetazolamide

CAS Number: 83280-65-3

TAK-715 odiamide hydrate C646 was used at 10TAK 715 is a potent p38 MAPK inhibitor. which displays potent inhibitory activity (inhibition of p38alpha, IC50 = 7. 1 nM; LPS stimulated release of TNF alpha from THP 1, IC50 = 48 nM; LPS induced TNF alpha production in mice, 87. 6% inhibition at 10 mg kg, po) and no inhibitory activity for major CYPs, including CYP3A4. TAK 715 was selected as a clinical candidate and is now under clinical investigation for the treatment of RA. Product information