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BI 653048 phosphate asaponin II InChiKey: AIQBYZOTCIQTGW-HXUWFJFHSA-N

SKU: 21647303302

4.8
USD100.00 USD126.00

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Description

InChiKey: AIQBYZOTCIQTGW-HXUWFJFHSA-N

the polyubiquitinated protein is degraded by proteasome

InChiKey: OWRCRVABZYJUES-FLJLGRLJSA-N

Formula: C16H14Cl2FN3S

InChi: InChI=1S/C32H44O8/c1-17(33)40-27(2

BI 653048 phosphate asaponin II InChiKey: AIQBYZOTCIQTGW-HXUWFJFHSA-NBI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms activity and reduces affinity for the hERG ion channel (IC50>30 M). BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.

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