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It inhibits PHD2 with an IC50 ~21 nM
Formula: C22H23Cl2N3O3
4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H
except an agonist for α4 and α6 subunit-containing ones
InChi: InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19
3α, 21-Dihydroxy-5α-pregnan-20-one 064 It inhibits PHD2 with an3,21 Dihydroxy 5 pregnan 20 one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3,21 Dihydroxy 5 pregnan 20 one potentiates neuronal response to low concentrations of GABA at 41 GABAA receptors in vitro. Product information CAS Number: 567 02 2 Molecular Weight: 334. 49 Formula: C21H34O3 Chemical Name: 1 [(1S,3aS,3bR,5aS,7R,9aS,9bS,11aS) 3a,3b,5a,9b tetrahydrogenio 7 hydroxy 9a,11a dimethyl hexadecahydro 1H
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