C-178 Catalog No.:M17037-C AKOS-22 inhibits both VDAC1 oligomerization

AKOS-22 inhibits both VDAC1 oligomerization and apoptosis in a concentration-dependent manner

4R)-1-[(2S)-2-(2-{2-[2-(2-{2-[(9S)-7-(4-chlorophenyl)-4

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma

such as BMP4

Smiles: CC(C)[C@H](NC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

C-178 Catalog No.:M17037-C AKOS-22 inhibits both VDAC1 oligomerizationC 178 is a potent and selective covalent inhibitor of STING. C 178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. Product information CAS Number: 329198 87 0 Molecular Weight: 322. 27 Formula: C17H10N2O5 Chemical Name: 5 nitro N {8 oxatricyclo[7. 4. 0. 0,]trideca 1(13),2,4,6,9,11 hexaen 5 yl}furan 2 carboxamide Smiles: [O ][N+](=O)C1=CC=C(O1)C(=O)NC1C=C2OC3=CC=CC=C3C2=CC=1 InChiKey: