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199(1):9-17
Mol Cell Endocrinol
It blocks Wnt-dependent phosphorylation of Lrp6 receptor and Dvl2
BI 1482694
Eur J Contracept Reprod Health Care
Cabazitaxel ndustin B 199(1):9-17Cabazitaxel is a semi synthetic derivative of the natural taxoid 10 deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2 M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane associated, multidrug resistance