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and 160 μM
Smiles: COC1CC(/C=C/C2=CC3OCOC=3C=C2)OC(=O)C=1
N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1 (HY-131188)
Smiles: OC(=O)COC[C@@H]1CC[C@@H](COC(=O)N(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1
Smiles: OC1=CC(O)=CC2O[C@@H]([C@@H](CC1=2)OC(=O)C1C=C(O)C(O)=C(O)C=1)C1=CC=C(O)C(O)=C1
PNU112455A hydrochloride analog 1 and 160 μMPNU112455A hydrochloride is an ATP competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3. 6 and 3. 2 M, respectively. Product information CAS Number: 21886 12 4 Molecular Weight: 301. 75 Formula: C10H12ClN5O2S Chemical Name: 4 [(6 aminopyrimidin 4 yl)amino]benzene 1 sulfonamide hydrochloride Smiles: Cl. NC1=CC(NC2=CC=C(C=C2)S(N)(=O)=O)=NC=N1 InChiKey: XBXQRCJKDCEQBS UHFFFAOYSA N InChi:
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