![A-381393 Size:Contact sales@xcessbio.com for quotation Selectively displaces [3H]clozapine from DREADDs](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M20762_1635205233.gif?v=1635205234)
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Selectively displaces [3H]clozapine from DREADDs in vivo
the numbers of B or T lymphocytes in the tumor-bearing lungs and spleens of treated mice is not affected
InChiKey: VFAFYBVPGKPJDO-UHFFFAOYSA-N
a signature event during apoptosis
TM-N1324 has reasonably good aqueous solubility (65 μM at pH 7
A-381393 Size:Contact [email protected] for quotation Selectively displaces [3H]clozapine from DREADDsA 381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist, with Kis of 1. 5, 1. 9 and 1. 6 nM for human dopamine D4. 4, D4. 2, and D4. 7 receptor, respectively, >2700 fold selectivity over D1, D2, D3 and D5 dopamine receptors. A 381393 shows moderate affinity for 5 HT2A (Ki, 370 nM). Product information CAS Number: 726174 00 1 Molecular Weight: 320. 43 Formula: C20H24N4 Chemical Name: 2 {[4 (3,4 dimethylphenyl)piperazin 1