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6-naphthyridin-6(5H)-yl)ethan-1-one hydrochloride
21561-09-1
31 nM in Neuro2A cells
InChi: InChI=1S/C12H17NO2/c1-4-9(2)10-7-5-6-8-11(10)15-12(14)13-3/h5-9H
InChiKey: BHIAIPWSVYSKJS-UHFFFAOYSA-N
CHM-1 icalcitol 6-naphthyridin-6(5H)-yl)ethan-1-one hydrochlorideCHM 1, a microtubule destabilizing agent, inhibits tubulin polymerization. CHM 1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM 1 induces growth inhibition and apoptosis via G2 M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity. Product information CAS Number: 154554 41 3 Molecular Weight: 283. 25 Formula: C16H10FNO3 Chemical Name: 6 (2 fluorophenyl)