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exhibits only background levels of caspase-3/7 activity
CPI203 could be dosed to the mice by oral administration at 5 mg/kg twice per day for 7 days
Jian-Ting Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation
including Aurora kinase A
inhibition of DDX3 by RK-33 promotes tumor regression
Vinblastine sulfate Size:Solid 2 mg exhibits only background levels ofVinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin dependent Ca++ transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
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