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CAS Number: 22260-51-1
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) inhibits MELK (IC50=38 nM)
and good bioavailability in all species
C-178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human
Smiles: CC1=CSC(Cl)=C1NC1NC2=CC=CC=C2N=1
LP-533401 Size:Contact [email protected] for quotation CAS Number: 22260-51-1LP 533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. LP 533401 completely inhibits serotonin production in Tph1expressing cells (RBL2H3 cells) at a dose of 1 M. Oral administration once daily for up to 6 weeks of this small molecule prevents the development of and fully rescues, in a dose dependent manner, osteoporosis in ovariectomized rodents because of an isolated increase in bone formation.
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