Phenformin Hydrochloride Catalog No.:M11294-10 Smiles: CC1N=CSC=1C1C=CC(=CC=1)[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCCCCN(CCOC1C=CC(=CC=1)C(=O)C1=C(SC2=CC(O)=CC=C21)C1C=CC(O)=CC=1)CC)C(C)(C)C

Smiles: CC1N=CSC=1C1C=CC(=CC=1)[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCCCCN(CCOC1C=CC(=CC=1)C(=O)C1=C(SC2=CC(O)=CC=C21)C1C=CC(O)=CC=1)CC)C(C)(C)C

therefore does not affect the wild-type protein

Molecular Weight: 974

vomiting and diarrhoea were reported with increasing doses and they limited dose escalation

AG14361 induces caspase 3/7 activation and cell cycle abnormalities

Phenformin Hydrochloride Catalog No.:M11294-10 Smiles: CC1N=CSC=1C1C=CC(=CC=1)[C@H](C)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)COCCCCCN(CCOC1C=CC(=CC=1)C(=O)C1=C(SC2=CC(O)=CC=C21)C1C=CC(O)=CC=1)CC)C(C)(C)CPhenformin Hydrochloride is the hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. It is potent to lower blood glucose concentrations in patients with non insulin dependent diabetes mellitus. Phenformin Hydrochloride improves insulin sensitivity and decrease insulin resistance by inhibiting complex 1 of the mitochondrial respiratory chain and inducing AMP activated protein