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is a novel noncyclic nucleotide EPAC antagonist that is capable of specifically blocking intracellular EPAC-mediated Rap1 activation and Akt phosphorylation
Pfister SX
5-2 μM final concentration in cell culture
5 mg/kg dissolved in 0
25(10):3164-3175
WY-14643 - CAS# 50892-23-4 Catalog No.:M6460-2 is a novel noncyclic nucleotideWY 14643, also known as pirinixic acid, CAS No. 50892 23 4, is a selective PPAR agonist. WY 14643 negatively inhibits NF B transcriptional activity and decreases the inflammatory response in vitro and in vivo. Product information CAS Number: 50892 23 4 Molecular Weight: 323. 80 Formula: C14H14ClN3O2S Synonym: WY 14643 WY 14643 WY14643 Pirinixic Acid Chemical Name: [[4 chloro 6 [(2,3 dimethylphenyl)amino] 2 pyrimidinyl]thio] acetic acid Smiles:
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