SRPIN340 fisoxazole Smiles: CC1(CCCNC(=O)NCCCC[C@H](N)C(O)=O)N=N1

Smiles: CC1(CCCNC(=O)NCCCC[C@H](N)C(O)=O)N=N1

1-7H3/t28-

86(5):969-77

InChi: InChI=1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30

2016 Sep 4

SRPIN340 fisoxazole Smiles: CC1(CCCNC(=O)NCCCC[C@H](N)C(O)=O)N=N1SRPIN340 is a selective serine arginine protein kinase (SRPK) 1 inhibitor with Ki = 0. 89 M. SRPK1 is a common binding partner of the E1^E4 protein of diverse human papillomavirus types. SRPK1 selective inhibitors could be a potentially novel topical (eye drop) therapeutic for wet AMD. Product information CAS Number: 218156 96 8 Molecular Weight: 349. 35 Formula: C18H18F3N3O Chemical Name: N [2 (piperidin 1 yl) 5 (trifluoromethyl)phenyl]pyridine 4