Gefitinib impurity 2 Catalog No.:M31681-C E2F1 is known to be

E2F1 is known to be interacted with by EGFR

CAS Number: 159997-94-1

InChiKey: ZAZKJZBWRNNLDS-UHFFFAOYSA-N

2010 May 12

Morizumi S

Gefitinib impurity 2 Catalog No.:M31681-C E2F1 is known to beGefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY 50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 246512 44 7 Molecular