Rapamycin - mTOR inhibitor. CAS# 53123-88-9 size:2mg solid Combining P5091 with lenalidomide

Combining P5091 with lenalidomide

CGK733 (10 μM) results in 1

BAM7 was used at 10-30 µM final concentration in vitro and in cellular assays

Smiles: CC1=NN=C2[C@H](CC(=O)NCC)N=C(C3=CC(=CC=C3N12)OC)C1C=CC(Cl)=CC=1

CAS Number: 418805-02-4

Rapamycin - mTOR inhibitor. CAS# 53123-88-9 size:2mg solid Combining P5091 with lenalidomideRapamycin, CAS No. 53123 88 9, is a potent and selective mTOR inhibitor. Rapamycin, in complex with the cytosolic protein FK binding protein 12 (FKBP12), inhibits mTOR Complex 1 (mTORC1) by binding to the FRB domain of mTor. Given the central roles mTor plays, Rapamycin showed diverse activities, including anti proliferative effects in cancer cells, immunosuppressive effect, lifespan extension in mice, improved cognition in the mouse model of autism