Scopine Hydrochloride 0185 4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazide

4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazide

Smiles: COC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C

enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats

Smiles: C[C@H](O)[C@H](CC)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(C=C1)OC[C@H]1C[C@@](CN2C=NC=N2)(OC1)C1=CC=C(F)C=C1F

11 xenograft tumor model in mice at well-tolerated dose schedules

Scopine Hydrochloride 0185 4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazideScopine HCl is a metabolite of the muscarinic antagonist scopolamine. Scopine binds to muscarinic acetylcholine receptors and is selective for muscarinic acetylcholine receptors over nicotinic acetylcholine receptors. It reduces hyperphagia induced by the antipsychotics loxapine and chlorpromazine. When conjugated to chlorambucil, scopine improves the blood brain barrier permeability of chlorambucil. Product information CAS Number: 85700 55 6