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InChi: InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6
rat) is a neuropeptide (62-76 residues of the CART peptide) with neurotransmitter-like effects
affording slightly better transcriptional efficacy
Smiles: C1=CC2C=CC=NC=2C2N=CC=CC=21
Ilginatinib hydrochloride shows potent inhibitory activity against cell lines JAK2V617F or MPLW515L mutations or the TEL-JAK2 fusion gene (expressing a constitutively activated JAK2) with IC50 of 11-120 nM
ARQ 621 Catalog No.:M19604-C InChi: InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6ARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule based ATPase motor protein involved in cell division. Anti tumor activity. ARQ 621 is a kinesin inhibitor. Product information CAS Number: 1095253 39 6 Molecular Weight: 552. 43 Formula: C28H24Cl2FN5O2 Chemical Name: N (3 aminopropyl) 3 chloro N [(1R) 1 [7 chloro 4 oxo 3 (phenylamino) 3,4 dihydroquinazolin 2 yl]but 3 yn 1 yl] 2 fluorobenzamide Smiles:
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