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with potent and broad-spectrum in vitro and in vivo cytotoxic activities
PubMed Central PMCID: PMC4216035
Formula: C18H18ClN3O3
Smiles: CC(C)C(NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(N)CCCCN)C(=O)NC(CC1=CC=CC=C1)C(O)=O
109(2):567-580
KRAS G12C inhibitor 5 Catalog No.:M17990-C with potent and broad-spectrum inKRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147. Product information CAS Number: 2158297 63 1 Molecular Weight: 551. 68 Formula: C32H37N7O2 Chemical Name: 2 [(2S) 4 (2 {[(2S) 1 methylpyrrolidin 2 yl]methoxy} 7 (naphthalen 1 yl) 5H,6H,7H,8H pyrido[3,4 d]pyrimidin 4 yl) 1 (prop 2 enoyl)piperazin 2 yl]acetonitrile Smiles: