Bis-PEG25-NHS ester onamide 2 (TFA) blocks both the catalytic activity

blocks both the catalytic activity and scaffolding effects of PARP1

Formula: C13H14BrN3O

14 and < 5 for NOP

All other kinases tested have IC50 values 50-fold greater than that for CK2

with pDC50s of 7

Bis-PEG25-NHS ester onamide 2 (TFA) blocks both the catalytic activityBis PEG25 NHS ester is a PEG Alkyl ether based PROTAC linker can be used in the synthesis of PROTACs. Bis PEG25 NHS ester is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 2221948 96 3 Molecular Weight: 1413. 55 Formula: C62H112N2O33 Chemical Name: bis(2,5 dioxopyrrolidin 1 yl) 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76 pentacosaoxanonaheptacontanedioate