Mice treated with T56-LIMKi (60 mg/kg) shows a significant decrease in tumor volume compared to control
2009 Aug 1
InChi: InChI=1S/C27H44N4O5/c1-4-6-8-12-24(34)30-22(18-20-13-15-21(32)16-14-20)26(35)31-25(19(3)5-2)27(36)29-17-10-7-9-11-23(28)33/h13-16
MEK162 was used at 1 µM final concentration in vitro and in cellular assays
Pawlotsky JM
Phorbol 12-myristate 13-acetate - CAS# 16561-29-8 size:2mg solid Mice treated with T56-LIMKi (60Phorbol 12 myristate 13 acetate, CAS No. 16561 29 8, is a protein kinase C (PKC) agonist potentially for thetreatment of acute myeloid leukemia and cardiac fibrosis. Product information CAS Number: 16561 29 8 Molecular Weight: 616. 83 Formula: C36H56O8 Synonym: NSC 262244 PD 616 RP 323 PMA NSC 262244 PD 616 RP 323 NSC262244 PD616 RP323 Chemical Name: (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS) 9a acetoxy 4a,7b dihydroxy 3 ( hydroxymethyl) 1,1,6,8 tetramethyl 5