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ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2
Chemical Name: 2-{[4-({[4-methoxy-2-(trifluoromethyl)phenyl]methyl}carbamoyl)phenyl]methyl}butanoic acid
InChiKey: WLHOBCUVPMOXAT-UHFFFAOYSA-N
4-Thiazolecarboxamide
and bicuculline-induced seizures and 6-Hz “psychomotor” seizures with median effective dose (ED50) values of 151
AMG-Tie2-1 622C-1215 ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SKAMG Tie2 1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG Tie2 1 is a VEGFR2 inhibitor with an IC50 of 3 nM. Product information CAS Number: 870223 96 4 Molecular Weight: 479. 45 Formula: C25H20F3N5O2 Chemical Name: 4 methyl 3 ({3 [2 (methylamino)pyrimidin 4 yl]pyridin 2 yl}oxy) N [3 (trifluoromethyl)phenyl]benzamide Smiles: CC1=CC=C(C=C1OC1=NC=CC=C1C1=CC=NC(NC)=N1)C(=O)NC1=CC(=CC=C1)C(F)(F)F InChiKey: