Pay in 4 interest-free payments of $9.00 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
inhibits Nedd4
p53 activity
Smiles: COCCOC1N=C(C2=CC(Cl)=C(Cl)C=C2)N(N=1)C1C=CC(=CC=1)NC(=O)CCl
and the same pattern is observed in G2/M phase (29
17R)-6-ethyl-3
Abiraterone - CYP17 inhibitor Abiraterone (CB-7598). CAS# 154229-19-3 one Demethylase inhibits Nedd4Abiraterone, CAS No. 154229 19 3, is the first in class potent and selective CYP17 (cytochrome P450 17alpha hydroxylase 17, 20 lyase) inhibitor with IC50 ~4 nM. It was approved by US FDA in 2011 to treat castration resistant prostate cancer. As prostate cancer cells proliferate in response to androgen steroids, CYP17 inhibition is a new strategy to prevent androgen synthesis and treat lethal metastatic prostate cancer. In recent Nature publication,
US$ 49.00
US$ 72.00
US$ 11.95
US$ 17.95
US$ 49.00