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Discovery of I-BRD9
AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye
Formula: C6H13Cl2N3
likely functioning as a conformational lock
InChiKey: BYWLLSQTJBXAPV-UHFFFAOYSA-N
Gadoxetate Disodium 803430 Discovery of I-BRD9Gadoxetate Disodium (Gd EOB DTPA Disodium) is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system, which accumulates in normal, functioning hepatocytes. Gadoxetate Disodium (Gd EOB DTPA Disodium) is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1 weighted imaging. Product information CAS Number: 135326 22 6 Molecular Weight: 725. 71 Formula: C23H28GdN3Na2O11 Chemical Name:
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