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ZN-c3 shows excellent exposures and bioavailability in the dog PK study
Response to Benzocaine spray is observed in most animals tested
Smiles: CC(C)OC(=O)[C@@H](C)N[P@](=O)(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@](C)(F)[C@@H]1O)OC1=CC=CC=C1
3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13
3)4/h1-10H
CCG-100602 39572 ZN-c3 shows excellent exposures andCCG 100602 is a specific inhibitor of myocardin related transcription factor A serum response factor (MRTF A SRF) signaling. CCG 100602 specifically block MRTF A nuclear localization and thus inhibit the fibrogenic transcription factor SRF. Product information CAS Number: 1207113 88 9 Molecular Weight: 478. 82 Formula: C21H17ClF6N2O2 Chemical Name: 1 [3, 5 bis(trifluoromethyl)benzoyl] N (4 chlorophenyl)piperidine 3 carboxamide Smiles: