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Solamargin
Smiles: [O-][N+](=O)C1=CC(=CC=C1S(=O)(=O)N1CCN(CC1)C1=CC=NC2=CC(Cl)=CC=C12)[N+]([O-])=O
The inhibitor was efficacious in suppressing leukemic cell spreading and splenomegaly in a Ba/F3 JAK2(V617F) cell-driven mouse mechanistic model
4 hours) than the other HSP90 inhibitors (t1/2=7
The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels
Carmustine Catalog No.:M9844-10 SolamarginCarmustine is antineoplastic nitrosourea. Carmustine alkylates and cross links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood brain barrier readily. Product information CAS Number: 154 93 8 Molecular Weight: 214. 05