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Metolazone uolin-1 Binding Modes of Small-Molecule Inhibitors

SKU: 8239234920

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Description

Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2

CAS Number: 1127442-82-3

InChiKey: JUGOREOARAHOCO-UHFFFAOYSA-M

in antiretroviral-naive patients)

Harnessing Allostery: A Novel Approach to Drug Discovery[J]

Metolazone uolin-1 Binding Modes of Small-Molecule InhibitorsMetolazone is a thiazide like diuretic. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide,

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