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Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C RS-8359 shows little affinity for

SKU: 83018835970

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Description

RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect

a volatile compound

InChiKey: HYWXBDQAYLPMIX-UHFFFAOYSA-N

Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors

C4H4O4/c2*1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5

Epidermal Growth Factor Receptor Peptide (985-996) Catalog No.:M23036-C RS-8359 shows little affinity forEGFR (epidermal growth factor receptor) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor . EGFR dimerization stimulates its intrinsic intracellular protein tyrosine kinase activity. As a result, autophosphorylation of several tyrosine (Y) residues on the C terminal domain of EGFR occurs. These include Y992, Y1045, Y1068, Y1148 and Y1173. This

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