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Advancements in the Development of non-BET Bromodomain Chemical Probes
liver fibrosis
Malmquist NA
GSK1904529A (72 h) inhibits tumor cells proliferation with IC50s ranges from 35 nM to >30 μM
Smiles: COC1C=C2C3C(NC2=CC=1C1=C(C)ON=C1C)=NC(=NC=3NC1=CC(=NN1CC)C1CC1)C(=O)NCCCC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
(S, R, S)-AHPC-C1-Br Catalog No.:M13078-2 Advancements in the Development of(S,R,S) AHPC C1 Br is a synthesized E3 ligase ligand linker conjugate that incorporates the (S,R,S) AHPC based VHL ligand and a linker used in PROTAC technology. Product information CAS Number: 2379404 33 6 Molecular Weight: 551. 50 Formula: C24H31BrN4O4S Chemical Name: (2S,4R) 1 [(2S) 2 (2 bromoacetamido) 3,3 dimethylbutanoyl] 4 hydroxy N {[4 (4 methyl 1,3 thiazol 5 yl)phenyl]methyl}pyrrolidine 2 carboxamide Smiles:
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