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PLX-4720 treatment at 30 mg/kg/day significant inhibits the tumor growth of 8505c xenografts by >90%
for 12 hours) causes chromosomal fragmentation in HeLa cells
3-dichlorophenyl)-N-{[2-(pyridin-2-yloxy)phenyl]methyl}-1H-1
InChiKey: QNLLWVSHZXSUNF-HVSPQWTBSA-N
Akt at T308) at concentrations that matched those that inhibited cell growth
N1-Acetylspermidine hydrochloride 955303 PLX-4720 treatment at 30 mg/kg/dayN1 Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1 acetylspermine is the substrate for the polyamine oxidase (PAO). N1 Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1 acetylspermidine shows cleavage efficiency at apurinic sites in DNA. Product information CAS Number: 34450 16 3 Molecular Weight: 260. 20 Formula: C9H23Cl2N3O Chemical Name: N {3 [(4
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