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77 μM and more than 100-fold selectivity over other GRKs
Formula: C30H39ClN6O4S2
Treatment with TRC051384 results in significant dose-dependent increase in HSF1 transcriptional activity and recovery of luciferase activity
6 nM and 0
21-bis(propan-2-yl)-1
Almotriptan o cholesterol 77 μM and more thanAlmotriptan is a 5 HT1B 1D receptor agonist used to treat migraine. IC50: Target: 5 hydroxytryptamine1B 1D (5 HT1B 1D) ReceptorAlmotriptan is a selective 5 hydroxytryptamine1B 1D (5 HT1B 1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low nanomolar affinity for the 5 HT(1B) and 5 HT(1D) receptors in several species, including the human, while affinity for 5 HT receptors other than 5 HT(1B 1D) was clearly
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