MA-2029 11194 Total Synthesis of Hispidulin and

Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene KinasePim-1

Kersten MJ

It inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression

Solubility: DMSO : ≥ 33 mg/mL (99

Smiles: CCC1CCC(=O)O1

MA-2029 11194 Total Synthesis of Hispidulin andMA 2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4. 9 nM). MA 2029 is selective for the motilin receptor over various other receptors and ion channels. MA 2029 may be useful for gastrointestinal disorders associated with disturbed gastrointestinal motility. Product information CAS Number: 287206 61 5 Molecular Weight: 556. 71 Formula: C31H45FN4O4 Chemical Name: (Z,2S) N [(1S) 2 (3 tert butyl 4 hydroxyphenyl) 1