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PubMed PMID: 27836974
which may yield a potential cancer therapeutic by targeting the survivin protein directly
Solubility: DMSO : 10 mg/mL (7
InChi: InChI=1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1
7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2
PROTAC BET degrader-2 EE788 PubMed PMID: 27836974PROTAC BET degrader 2 is a highly potent degrader of Bromodomain and Extra Terminal (BET) proteins with an IC50 value of 9. 6 nM in cell growth inhibition in the RS4; 11 cells and capable of achieving tumor regression. Product information CAS Number: 2093388 33 9 Molecular Weight: 770. 84 Formula: C41H42N10O6 Chemical Name: 4 [(3 cyclopropyl 1 ethyl 1H pyrazol 5 yl)amino] 7 (3, 5 dimethyl 1, 2 oxazol 4 yl) N {3 [2 (2, 6 dioxopiperidin 3 yl) 1 oxo 2, 3
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